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Ankyrin repeat domain-containing protein SOWAHD (SOWAHD)

Homo sapiens — UniProt A6NJG2

Gene: SOWAHDHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Ankyrin repeat domain-containing protein SOWAHD (SOWAHD) is a protein from Homo sapiens identified by UniProt accession A6NJG2, 315 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

  • UniProt accession: A6NJG2; gene symbol SOWAHD.
  • Organism: Homo sapiens.
  • Length: 315 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, COVID-19 and cutaneous lupus erythematosus.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameAnkyrin repeat domain-containing protein SOWAHD
UniProt accessionA6NJG2
GeneSOWAHD
OrganismHomo sapiens
Length315 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (5)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.44
  • COVID-19 · score 0.01
  • cutaneous lupus erythematosus · score 0.01
  • papillary thyroid carcinoma · score 0.00
  • Sepsis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-A6NJG2-F1alphafoldPREDICTED65.06—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NJG2.

Amino-acid sequence (315 residues)

MAQLGGAANR APTASLAPTS QSLRCAPQPR PSRADTGSLG RYWGKAAAAA SREHPFPGTL MHSAAGSGRR RGALRELLGL QRAAPAGWLS EERAEELGGP SGPGSSRLCL EPREHAWILA AAEGRYEVLR ELLEAEPELL LRGDPITGYS VLHWLAKHGR HEELILVHDF ALRRGLRLDV SAPGSGGLTP LHLAALQGHD MVIKVLVGAL GADATRRDHS GHRACHYLRP DAPWRLRELS GAEEWEMESG SGCTNLNNNS SGTTAWRAAS AVGATAVETS RRVAASRTKA KDTAGSRVAQ MHSLFRHLFP SFQDR

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SOWAHD?

The strongest Open Targets associations for SOWAHD are neurodegenerative disease, COVID-19, cutaneous lupus erythematosus, papillary thyroid carcinoma and Sepsis.

How long is the SOWAHD protein?

The Homo sapiens SOWAHD protein (UniProt A6NJG2) is 315 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtA6NJG2
GeneSOWAHD
OrganismHomo sapiens
Length315
Binders0
Diseases5
View on UniProt