Uncharacterized protein C11orf86 (C11orf86)
Homo sapiens — UniProt A6NJI1
Data last refreshed: (UniProt release unknown)
Key facts
Uncharacterized protein C11orf86 (C11orf86) is a protein from Homo sapiens identified by UniProt accession A6NJI1, 115 residues long. MolForge cross-references it against 0 known binders and 119 disease associations.
- UniProt accession: A6NJI1; gene symbol C11orf86.
- Organism: Homo sapiens.
- Length: 115 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, Barrett's esophagus and glycogen storage disease VI.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Uncharacterized protein C11orf86 |
|---|---|
| UniProt accession | A6NJI1 |
| Gene | C11orf86 |
| Organism | Homo sapiens |
| Length | 115 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (119)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.14
- Barrett's esophagus · score 0.08
- glycogen storage disease VI · score 0.06
- MODY · score 0.06
- erythrocyte count · score 0.05
- obesity due to melanocortin 4 receptor deficiency · score 0.05
- coronary artery disease, autosomal dominant 2 · score 0.05
- Hyperlipoproteinemia type 1 · score 0.05
- hypoinsulinemic hypoglycemia and body hemihypertrophy · score 0.05
- CIDEC-related familial partial lipodystrophy · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NJI1-F1 | alphafold | PREDICTED | 64.31 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NJI1.
Amino-acid sequence (115 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C11orf86?
The strongest Open Targets associations for C11orf86 are heel bone mineral density, Barrett's esophagus, glycogen storage disease VI, MODY and erythrocyte count.
How long is the C11orf86 protein?
The Homo sapiens C11orf86 protein (UniProt A6NJI1) is 115 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NJI1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NJI1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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