Nuclear pore complex-interacting protein family member B13 (NPIPB13)
Homo sapiens — UniProt A6NJU9
Data last refreshed: (UniProt release unknown)
Key facts
Nuclear pore complex-interacting protein family member B13 (NPIPB13) is a protein from Homo sapiens identified by UniProt accession A6NJU9, 1138 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.
- UniProt accession: A6NJU9; gene symbol NPIPB13.
- Organism: Homo sapiens.
- Length: 1138 amino acids.
- Top disease associations (Open Targets): mean platelet volume, FEV/FVC ratio and electrocardiography.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nuclear pore complex-interacting protein family member B13 |
|---|---|
| UniProt accession | A6NJU9 |
| Gene | NPIPB13 |
| Organism | Homo sapiens |
| Length | 1138 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (5)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.07
- FEV/FVC ratio · score 0.07
- electrocardiography · score 0.04
- creatinine measurement · score 0.03
- Hodgkins lymphoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NJU9-F1 | alphafold | PREDICTED | 43.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NJU9.
Amino-acid sequence (1138 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NPIPB13?
The strongest Open Targets associations for NPIPB13 are mean platelet volume, FEV/FVC ratio, electrocardiography, creatinine measurement and Hodgkins lymphoma.
How long is the NPIPB13 protein?
The Homo sapiens NPIPB13 protein (UniProt A6NJU9) is 1138 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NJU9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NJU9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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