Transmembrane protein 238-like (TMEM238L)
Homo sapiens — UniProt A6NJY4
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 238-like (TMEM238L) is a protein from Homo sapiens identified by UniProt accession A6NJY4, 79 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: A6NJY4; gene symbol TMEM238L.
- Organism: Homo sapiens.
- Length: 79 amino acids.
- Top disease associations (Open Targets): colorectal cancer, colorectal adenoma and intracerebral hemorrhage.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 238-like |
|---|---|
| UniProt accession | A6NJY4 |
| Gene | TMEM238L |
| Organism | Homo sapiens |
| Length | 79 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- colorectal cancer · score 0.39
- colorectal adenoma · score 0.20
- intracerebral hemorrhage · score 0.15
- breast cancer · score 0.07
- gonorrhea · score 0.07
- musculoskeletal system disease · score 0.04
- neoplasm · score 0.04
- hepatocellular carcinoma · score 0.04
- arterial stiffness measurement · score 0.03
- cancer · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NJY4-F1 | alphafold | PREDICTED | 84.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NJY4.
Amino-acid sequence (79 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM238L?
The strongest Open Targets associations for TMEM238L are colorectal cancer, colorectal adenoma, intracerebral hemorrhage, breast cancer and gonorrhea.
How long is the TMEM238L protein?
The Homo sapiens TMEM238L protein (UniProt A6NJY4) is 79 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NJY4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NJY4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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