Coiled-coil domain-containing protein 85C (CCDC85C)
Homo sapiens — UniProt A6NKD9
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil domain-containing protein 85C (CCDC85C) is a protein from Homo sapiens identified by UniProt accession A6NKD9, 419 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.
- UniProt accession: A6NKD9; gene symbol CCDC85C.
- Organism: Homo sapiens.
- Length: 419 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, intellectual developmental disorder with hypertelorism and distinctive facies and coronary artery disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil domain-containing protein 85C |
|---|---|
| UniProt accession | A6NKD9 |
| Gene | CCDC85C |
| Organism | Homo sapiens |
| Length | 419 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (33)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- intellectual developmental disorder with hypertelorism and distinctive facies · score 0.17
- coronary artery disease · score 0.09
- orthopedic nursing · score 0.08
- hepatocellular carcinoma · score 0.05
- lymphocyte percentage of leukocytes · score 0.03
- Chudley-McCullough syndrome · score 0.03
- lymphocyte count · score 0.03
- cerebral amyloid angiopathy, APP-related · score 0.03
- eosinophil count · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NKD9-F1 | alphafold | PREDICTED | 68.12 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NKD9.
Amino-acid sequence (419 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCDC85C?
The strongest Open Targets associations for CCDC85C are neurodegenerative disease, intellectual developmental disorder with hypertelorism and distinctive facies, coronary artery disease, orthopedic nursing and hepatocellular carcinoma.
How long is the CCDC85C protein?
The Homo sapiens CCDC85C protein (UniProt A6NKD9) is 419 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NKD9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NKD9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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