Transmembrane protein 200C (TMEM200C)
Homo sapiens — UniProt A6NKL6
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 200C (TMEM200C) is a protein from Homo sapiens identified by UniProt accession A6NKL6, 621 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: A6NKL6; gene symbol TMEM200C.
- Organism: Homo sapiens.
- Length: 621 amino acids.
- Top disease associations (Open Targets): mathematical ability, smoking status measurement and self reported educational attainment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 200C |
|---|---|
| UniProt accession | A6NKL6 |
| Gene | TMEM200C |
| Organism | Homo sapiens |
| Length | 621 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.46
- smoking status measurement · score 0.41
- self reported educational attainment · score 0.41
- musculoskeletal system disease · score 0.40
- smoking initiation · score 0.33
- attention deficit hyperactivity disorder · score 0.32
- antisocial behaviour measurement · score 0.32
- substance abuse · score 0.32
- cognitive function measurement · score 0.32
- cutaneous mastocytosis · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NKL6-F1 | alphafold | PREDICTED | 49.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NKL6.
Amino-acid sequence (621 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM200C?
The strongest Open Targets associations for TMEM200C are mathematical ability, smoking status measurement, self reported educational attainment, musculoskeletal system disease and smoking initiation.
How long is the TMEM200C protein?
The Homo sapiens TMEM200C protein (UniProt A6NKL6) is 621 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NKL6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NKL6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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