Speedy protein E3 (SPDYE3)
Homo sapiens — UniProt A6NKU9
Data last refreshed: (UniProt release unknown)
Key facts
Speedy protein E3 (SPDYE3) is a protein from Homo sapiens identified by UniProt accession A6NKU9, 549 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: A6NKU9; gene symbol SPDYE3.
- Organism: Homo sapiens.
- Length: 549 amino acids.
- Top disease associations (Open Targets): blood protein measurement, heel bone mineral density and monocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Speedy protein E3 |
|---|---|
| UniProt accession | A6NKU9 |
| Gene | SPDYE3 |
| Organism | Homo sapiens |
| Length | 549 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.16
- heel bone mineral density · score 0.09
- monocyte count · score 0.09
- platelet count · score 0.09
- electrocardiography · score 0.07
- self reported educational attainment · score 0.07
- serum albumin measurement · score 0.07
- grip strength measurement · score 0.06
- age-related macular degeneration · score 0.05
- atrophic macular degeneration · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NKU9-F1 | alphafold | PREDICTED | 49.99 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NKU9.
Amino-acid sequence (549 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPDYE3?
The strongest Open Targets associations for SPDYE3 are blood protein measurement, heel bone mineral density, monocyte count, platelet count and electrocardiography.
How long is the SPDYE3 protein?
The Homo sapiens SPDYE3 protein (UniProt A6NKU9) is 549 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NKU9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NKU9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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