Protein shisa-like-2B (SHISAL2B)
Homo sapiens — UniProt A6NKW6
Data last refreshed: (UniProt release unknown)
Key facts
Protein shisa-like-2B (SHISAL2B) is a protein from Homo sapiens identified by UniProt accession A6NKW6, 160 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.
- UniProt accession: A6NKW6; gene symbol SHISAL2B.
- Organism: Homo sapiens.
- Length: 160 amino acids.
- Top disease associations (Open Targets): body mass index, body fat percentage and body weight.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein shisa-like-2B |
|---|---|
| UniProt accession | A6NKW6 |
| Gene | SHISAL2B |
| Organism | Homo sapiens |
| Length | 160 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (47)
Diseases linked to this target (Open Targets).
- body mass index · score 0.33
- body fat percentage · score 0.32
- body weight · score 0.30
- chronotype measurement · score 0.25
- sex hormone-binding globulin measurement · score 0.24
- aspartate aminotransferase measurement · score 0.24
- high density lipoprotein cholesterol measurement · score 0.24
- serum alanine aminotransferase measurement · score 0.24
- low density lipoprotein triglyceride measurement · score 0.24
- cognitive function measurement · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NKW6-F1 | alphafold | PREDICTED | 69.40 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NKW6.
Amino-acid sequence (160 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SHISAL2B?
The strongest Open Targets associations for SHISAL2B are body mass index, body fat percentage, body weight, chronotype measurement and sex hormone-binding globulin measurement.
How long is the SHISAL2B protein?
The Homo sapiens SHISAL2B protein (UniProt A6NKW6) is 160 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NKW6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NKW6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.