Putative solute carrier family 22 member 31 (SLC22A31)
Homo sapiens — UniProt A6NKX4
Data last refreshed: (UniProt release unknown)
Key facts
Putative solute carrier family 22 member 31 (SLC22A31) is a protein from Homo sapiens identified by UniProt accession A6NKX4, 556 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.
- UniProt accession: A6NKX4; gene symbol SLC22A31.
- Organism: Homo sapiens.
- Length: 556 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Red cell distribution width and response to tofacitinib.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Putative solute carrier family 22 member 31 |
|---|---|
| UniProt accession | A6NKX4 |
| Gene | SLC22A31 |
| Organism | Homo sapiens |
| Length | 556 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (33)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- Red cell distribution width · score 0.29
- response to tofacitinib · score 0.15
- Herpes Zoster · score 0.15
- cystatin C measurement · score 0.13
- neutrophil count · score 0.11
- lymphocyte count · score 0.07
- creatinine measurement · score 0.06
- lymphocyte percentage of leukocytes · score 0.06
- sunburn · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NKX4-F1 | alphafold | PREDICTED | 78.15 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NKX4.
Amino-acid sequence (556 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC22A31?
The strongest Open Targets associations for SLC22A31 are neurodegenerative disease, Red cell distribution width, response to tofacitinib, Herpes Zoster and cystatin C measurement.
How long is the SLC22A31 protein?
The Homo sapiens SLC22A31 protein (UniProt A6NKX4) is 556 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NKX4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NKX4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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