Tripartite motif-containing protein 64C (TRIM64C)
Homo sapiens — UniProt A6NLI5
Data last refreshed: (UniProt release unknown)
Key facts
Tripartite motif-containing protein 64C (TRIM64C) is a protein from Homo sapiens identified by UniProt accession A6NLI5, 450 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: A6NLI5; gene symbol TRIM64C.
- Organism: Homo sapiens.
- Length: 450 amino acids.
- Top disease associations (Open Targets): high density lipoprotein cholesterol measurement, systolic blood pressure and alcohol consumption measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tripartite motif-containing protein 64C |
|---|---|
| UniProt accession | A6NLI5 |
| Gene | TRIM64C |
| Organism | Homo sapiens |
| Length | 450 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- high density lipoprotein cholesterol measurement · score 0.28
- systolic blood pressure · score 0.26
- alcohol consumption measurement · score 0.19
- hypertension · score 0.18
- physical activity · score 0.16
- HDL cholesterol change measurement · score 0.16
- urinary metabolite measurement · score 0.15
- intraocular pressure measurement · score 0.14
- blood protein measurement · score 0.13
- Agents acting on the renin-angiotensin system use measurement · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NLI5-F1 | alphafold | PREDICTED | 83.68 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NLI5.
Amino-acid sequence (450 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TRIM64C?
The strongest Open Targets associations for TRIM64C are high density lipoprotein cholesterol measurement, systolic blood pressure, alcohol consumption measurement, hypertension and physical activity.
How long is the TRIM64C protein?
The Homo sapiens TRIM64C protein (UniProt A6NLI5) is 450 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NLI5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NLI5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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