Ret finger protein-like 4A (RFPL4A)
Homo sapiens — UniProt A6NLU0
Data last refreshed: (UniProt release unknown)
Key facts
Ret finger protein-like 4A (RFPL4A) is a protein from Homo sapiens identified by UniProt accession A6NLU0, 287 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.
- UniProt accession: A6NLU0; gene symbol RFPL4A.
- Organism: Homo sapiens.
- Length: 287 amino acids.
- Top disease associations (Open Targets): Abnormal jaw morphology, age at menopause and carcinoma of liver and intrahepatic biliary tract.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ret finger protein-like 4A |
|---|---|
| UniProt accession | A6NLU0 |
| Gene | RFPL4A |
| Organism | Homo sapiens |
| Length | 287 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (5)
Diseases linked to this target (Open Targets).
- Abnormal jaw morphology · score 0.02
- age at menopause · score 0.02
- carcinoma of liver and intrahepatic biliary tract · score 0.02
- cancer · score 0.01
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NLU0-F1 | alphafold | PREDICTED | 91.12 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NLU0.
Amino-acid sequence (287 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RFPL4A?
The strongest Open Targets associations for RFPL4A are Abnormal jaw morphology, age at menopause, carcinoma of liver and intrahepatic biliary tract, cancer and neoplasm.
How long is the RFPL4A protein?
The Homo sapiens RFPL4A protein (UniProt A6NLU0) is 287 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NLU0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NLU0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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