Speedy protein E4 (SPDYE4)
Homo sapiens — UniProt A6NLX3
Data last refreshed: (UniProt release unknown)
Key facts
Speedy protein E4 (SPDYE4) is a protein from Homo sapiens identified by UniProt accession A6NLX3, 237 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.
- UniProt accession: A6NLX3; gene symbol SPDYE4.
- Organism: Homo sapiens.
- Length: 237 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, sex hormone-binding globulin measurement and neuronal ceroid lipofuscinosis 1.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Speedy protein E4 |
|---|---|
| UniProt accession | A6NLX3 |
| Gene | SPDYE4 |
| Organism | Homo sapiens |
| Length | 237 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (5)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.25
- sex hormone-binding globulin measurement · score 0.06
- neuronal ceroid lipofuscinosis 1 · score 0.03
- breast carcinoma · score 0.01
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NLX3-F1 | alphafold | PREDICTED | 77.34 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NLX3.
Amino-acid sequence (237 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPDYE4?
The strongest Open Targets associations for SPDYE4 are neurodegenerative disease, sex hormone-binding globulin measurement, neuronal ceroid lipofuscinosis 1, breast carcinoma and neoplasm.
How long is the SPDYE4 protein?
The Homo sapiens SPDYE4 protein (UniProt A6NLX3) is 237 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NLX3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NLX3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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