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Protein FAM170B (FAM170B)

Homo sapiens — UniProt A6NMN3

Gene: FAM170BHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Protein FAM170B (FAM170B) is a protein from Homo sapiens identified by UniProt accession A6NMN3, 283 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

  • UniProt accession: A6NMN3; gene symbol FAM170B.
  • Organism: Homo sapiens.
  • Length: 283 amino acids.
  • Top disease associations (Open Targets): cortical thickness, monocyte count and basophil count.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProtein FAM170B
UniProt accessionA6NMN3
GeneFAM170B
OrganismHomo sapiens
Length283 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (38)

Diseases linked to this target (Open Targets).

  • cortical thickness · score 0.25
  • monocyte count · score 0.23
  • basophil count · score 0.20
  • diet measurement · score 0.18
  • mean corpuscular volume · score 0.18
  • IGF-1 measurement · score 0.17
  • cortical surface area measurement · score 0.17
  • leukocyte count · score 0.16
  • insulin like growth factor measurement · score 0.16
  • neuroimaging measurement · score 0.15

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-A6NMN3-F1alphafoldPREDICTED61.46—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NMN3.

Amino-acid sequence (283 residues)

MKCYFTDHRG EQSPTDGTTL SLTSPESTEE SVEVFWPGTI QREGSSPRPG PAIPREEGLY FAARDRGMRD WSSSPSSESS EYQSYSQYQS CCSCMCDEDN AAPQSVCAFY THVQTVRGVA VAWETEAGFE PVTRKPRIHE AQFIKRQRWN GSSFEMASNT DMRWDLEACK SNCSPEPEDI DLLECCLQEL REPPDWLVTT NYGVRCVACC RVLPSLDALL EHAQHGIREG FSCQIFFEEM LERRRAQGQA HDQQLEEEQS PSDNSECSRP QGEVLSAQQQ EKQ

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with FAM170B?

The strongest Open Targets associations for FAM170B are cortical thickness, monocyte count, basophil count, diet measurement and mean corpuscular volume.

How long is the FAM170B protein?

The Homo sapiens FAM170B protein (UniProt A6NMN3) is 283 amino acids long.

Browse: Targets: F · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtA6NMN3
GeneFAM170B
OrganismHomo sapiens
Length283
Binders0
Diseases38
View on UniProt