Homeobox protein DBX1 (DBX1)
Homo sapiens — UniProt A6NMT0
Data last refreshed: (UniProt release unknown)
Key facts
Homeobox protein DBX1 (DBX1) is a protein from Homo sapiens identified by UniProt accession A6NMT0, 343 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.
- UniProt accession: A6NMT0; gene symbol DBX1.
- Organism: Homo sapiens.
- Length: 343 amino acids.
- Top disease associations (Open Targets): body height, response to glucocorticoid and FEV change measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Homeobox protein DBX1 |
|---|---|
| UniProt accession | A6NMT0 |
| Gene | DBX1 |
| Organism | Homo sapiens |
| Length | 343 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- body height · score 0.30
- response to glucocorticoid · score 0.27
- FEV change measurement · score 0.27
- appendicular lean mass · score 0.26
- t-tau:beta-amyloid 1-42 ratio measurement · score 0.26
- atrial fibrillation · score 0.15
- electrocardiography · score 0.15
- PR interval · score 0.13
- cortical surface area measurement · score 0.11
- atrial flutter · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NMT0-F1 | alphafold | PREDICTED | 61.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NMT0.
Amino-acid sequence (343 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DBX1?
The strongest Open Targets associations for DBX1 are body height, response to glucocorticoid, FEV change measurement, appendicular lean mass and t-tau:beta-amyloid 1-42 ratio measurement.
How long is the DBX1 protein?
The Homo sapiens DBX1 protein (UniProt A6NMT0) is 343 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NMT0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NMT0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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