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Sentan (SNTN)

Homo sapiens — UniProt A6NMZ2

Gene: SNTNHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Sentan (SNTN) is a protein from Homo sapiens identified by UniProt accession A6NMZ2, 147 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

  • UniProt accession: A6NMZ2; gene symbol SNTN.
  • Organism: Homo sapiens.
  • Length: 147 amino acids.
  • Top disease associations (Open Targets): gut microbiome measurement, chronotype measurement and diffuse plaque measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSentan
UniProt accessionA6NMZ2
GeneSNTN
OrganismHomo sapiens
Length147 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (13)

Diseases linked to this target (Open Targets).

  • gut microbiome measurement · score 0.31
  • chronotype measurement · score 0.04
  • diffuse plaque measurement · score 0.04
  • nasopharyngeal neoplasm · score 0.02
  • non-small cell lung carcinoma · score 0.02
  • lung adenocarcinoma · score 0.01
  • endometrial carcinoma · score 0.01
  • lung carcinoma · score 0.01
  • ovarian serous carcinoma · score 0.00
  • ovarian neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-A6NMZ2-F1alphafoldPREDICTED81.24—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NMZ2.

Amino-acid sequence (147 residues)

MGGCMHSTQD KSLHLEGDPN PSAAPTSTCA PRKMPKRISI SKQLASVKAL RKCSDLEKAI ATTALIFRNS SDSDGKLEKA IAKDLLQTQF RNFAEGQETK PKYREILSEL DEHTENKLDF EDFMILLLSI TVMSDLLQNI RNVKIMK

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SNTN?

The strongest Open Targets associations for SNTN are gut microbiome measurement, chronotype measurement, diffuse plaque measurement, nasopharyngeal neoplasm and non-small cell lung carcinoma.

How long is the SNTN protein?

The Homo sapiens SNTN protein (UniProt A6NMZ2) is 147 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtA6NMZ2
GeneSNTN
OrganismHomo sapiens
Length147
Binders0
Diseases13
View on UniProt