Dorsal root ganglia homeobox protein (DRGX)
Homo sapiens — UniProt A6NNA5
Data last refreshed: (UniProt release unknown)
Key facts
Dorsal root ganglia homeobox protein (DRGX) is a protein from Homo sapiens identified by UniProt accession A6NNA5, 263 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.
- UniProt accession: A6NNA5; gene symbol DRGX.
- Organism: Homo sapiens.
- Length: 263 amino acids.
- Top disease associations (Open Targets): appendicular lean mass, body height and protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dorsal root ganglia homeobox protein |
|---|---|
| UniProt accession | A6NNA5 |
| Gene | DRGX |
| Organism | Homo sapiens |
| Length | 263 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- appendicular lean mass · score 0.20
- body height · score 0.12
- protein measurement · score 0.08
- calcium measurement · score 0.07
- PR interval · score 0.05
- pancreatic adenocarcinoma · score 0.04
- Meacham syndrome · score 0.03
- Testicular regression syndrome · score 0.03
- Senior-Boichis syndrome · score 0.03
- Cardiac-urogenital syndrome · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NNA5-F1 | alphafold | PREDICTED | 66.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NNA5.
Amino-acid sequence (263 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DRGX?
The strongest Open Targets associations for DRGX are appendicular lean mass, body height, protein measurement, calcium measurement and PR interval.
How long is the DRGX protein?
The Homo sapiens DRGX protein (UniProt A6NNA5) is 263 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NNA5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NNA5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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