Tubulin polyglutamylase TTLL13 (TTLL13)
Homo sapiens — UniProt A6NNM8
Data last refreshed: (UniProt release unknown)
Key facts
Tubulin polyglutamylase TTLL13 (TTLL13) is a protein from Homo sapiens identified by UniProt accession A6NNM8, 815 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: A6NNM8; gene symbol TTLL13.
- Organism: Homo sapiens.
- Length: 815 amino acids.
- Top disease associations (Open Targets): polyp of colon, alkaline phosphatase measurement and serum gamma-glutamyl transferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tubulin polyglutamylase TTLL13 |
|---|---|
| UniProt accession | A6NNM8 |
| Gene | TTLL13 |
| Organism | Homo sapiens |
| Length | 815 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- polyp of colon · score 0.26
- alkaline phosphatase measurement · score 0.25
- serum gamma-glutamyl transferase measurement · score 0.05
- metabolite measurement · score 0.05
- neoplasm · score 0.01
- cancer · score 0.00
- bacterial disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6NNM8-F1 | alphafold | PREDICTED | 64.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NNM8.
Amino-acid sequence (815 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TTLL13?
The strongest Open Targets associations for TTLL13 are polyp of colon, alkaline phosphatase measurement, serum gamma-glutamyl transferase measurement, metabolite measurement and neoplasm.
How long is the TTLL13 protein?
The Homo sapiens TTLL13 protein (UniProt A6NNM8) is 815 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6NNM8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6NNM8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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