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Speedy protein E16 (SPDYE16)

Homo sapiens — UniProt A6NNV3

Gene: SPDYE16Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Speedy protein E16 (SPDYE16) is a protein from Homo sapiens identified by UniProt accession A6NNV3, 352 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

  • UniProt accession: A6NNV3; gene symbol SPDYE16.
  • Organism: Homo sapiens.
  • Length: 352 amino acids.
  • Top disease associations (Open Targets): CCL24 measurement, neuronal ceroid lipofuscinosis 1 and refractive error measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSpeedy protein E16
UniProt accessionA6NNV3
GeneSPDYE16
OrganismHomo sapiens
Length352 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (5)

Diseases linked to this target (Open Targets).

  • CCL24 measurement · score 0.06
  • neuronal ceroid lipofuscinosis 1 · score 0.03
  • refractive error measurement · score 0.02
  • osteoarthritis · score 0.02
  • polycystic ovary syndrome · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-A6NNV3-F1alphafoldPREDICTED59.89—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NNV3.

Amino-acid sequence (352 residues)

MDRTETRFRK RGQIKGKITT SRQPHPQNEQ SPQRSTSGYS LQEVVDDEVL GSSAPGVDPS PPCRSLGWKR KKEWSDESEE EPEKELAPEP EETWVVEMLC GLKMKLKQQR VSPILPEHHK DFNSQLAPGV DPSPPHRSFC WKRKREWWDE SEESLEEEPR KVLAPEPEEI WVVEMLCGLK MKLKRRRVSL VLPEHHEAFN RLLEDPVIKR FLAWDKDLRV SDKYLLAMVI AYFSRAGLPS WQYQRIHFFL ALYLANDMEE DDEDPKQNIF YFLYGKTRSR IPLVRNRRFQ LCRCMNPRAR KNRSQIALFQ KLRFQFFCSM SGRAWVSREE LEEIQAYDPE HWVWARDRAR LS

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SPDYE16?

The strongest Open Targets associations for SPDYE16 are CCL24 measurement, neuronal ceroid lipofuscinosis 1, refractive error measurement, osteoarthritis and polycystic ovary syndrome.

How long is the SPDYE16 protein?

The Homo sapiens SPDYE16 protein (UniProt A6NNV3) is 352 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtA6NNV3
GeneSPDYE16
OrganismHomo sapiens
Length352
Binders0
Diseases5
View on UniProt