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RIIa domain-containing protein 1 (RIIAD1)

Homo sapiens — UniProt A6NNX1

Gene: RIIAD1Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

RIIa domain-containing protein 1 (RIIAD1) is a protein from Homo sapiens identified by UniProt accession A6NNX1, 92 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

  • UniProt accession: A6NNX1; gene symbol RIIAD1.
  • Organism: Homo sapiens.
  • Length: 92 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, hemoglobin measurement and body fat percentage.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameRIIa domain-containing protein 1
UniProt accessionA6NNX1
GeneRIIAD1
OrganismHomo sapiens
Length92 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (20)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.37
  • hemoglobin measurement · score 0.11
  • body fat percentage · score 0.10
  • low density lipoprotein triglyceride measurement · score 0.08
  • high density lipoprotein cholesterol measurement · score 0.08
  • sex hormone-binding globulin measurement · score 0.08
  • serum alanine aminotransferase measurement · score 0.08
  • aspartate aminotransferase measurement · score 0.08
  • angina pectoris · score 0.05
  • calcium measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-A6NNX1-F1alphafoldPREDICTED90.37—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6NNX1.

Amino-acid sequence (92 residues)

METLPGLLQR PDPGALSAAQ LEQLRKFKIQ TRIANEKYLR THKEVEWLIS GFFREIFLKR PDNILEFAAD YFTDPRLPNK IHMQLIKDKK AA

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with RIIAD1?

The strongest Open Targets associations for RIIAD1 are neurodegenerative disease, hemoglobin measurement, body fat percentage, low density lipoprotein triglyceride measurement and high density lipoprotein cholesterol measurement.

How long is the RIIAD1 protein?

The Homo sapiens RIIAD1 protein (UniProt A6NNX1) is 92 amino acids long.

Browse: Targets: R · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtA6NNX1
GeneRIIAD1
OrganismHomo sapiens
Length92
Binders0
Diseases20
View on UniProt