Protein FAM177B (FAM177B)
Homo sapiens — UniProt A6PVY3
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAM177B (FAM177B) is a protein from Homo sapiens identified by UniProt accession A6PVY3, 158 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: A6PVY3; gene symbol FAM177B.
- Organism: Homo sapiens.
- Length: 158 amino acids.
- Top disease associations (Open Targets): appendicular lean mass, coronary artery bypass and cardiovascular disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAM177B |
|---|---|
| UniProt accession | A6PVY3 |
| Gene | FAM177B |
| Organism | Homo sapiens |
| Length | 158 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- appendicular lean mass · score 0.29
- coronary artery bypass · score 0.29
- cardiovascular disease · score 0.26
- coronary artery disease · score 0.13
- angina pectoris · score 0.11
- Barrett's esophagus · score 0.07
- esophageal adenocarcinoma · score 0.05
- myocardial infarction · score 0.04
- body fat percentage · score 0.02
- body height · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A6PVY3-F1 | alphafold | PREDICTED | 63.49 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A6PVY3.
Amino-acid sequence (158 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM177B?
The strongest Open Targets associations for FAM177B are appendicular lean mass, coronary artery bypass, cardiovascular disease, coronary artery disease and angina pectoris.
How long is the FAM177B protein?
The Homo sapiens FAM177B protein (UniProt A6PVY3) is 158 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A6PVY3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A6PVY3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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