Sine oculis-binding protein homolog (SOBP)
Homo sapiens — UniProt A7XYQ1
Data last refreshed: (UniProt release unknown)
Key facts
Sine oculis-binding protein homolog (SOBP) is a protein from Homo sapiens identified by UniProt accession A7XYQ1, 873 residues long. MolForge cross-references it against 0 known binders and 60 disease associations.
- UniProt accession: A7XYQ1; gene symbol SOBP.
- Organism: Homo sapiens.
- Length: 873 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, body height and Intellectual disability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sine oculis-binding protein homolog |
|---|---|
| UniProt accession | A7XYQ1 |
| Gene | SOBP |
| Organism | Homo sapiens |
| Length | 873 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (60)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.48
- body height · score 0.44
- Intellectual disability · score 0.40
- protein measurement · score 0.34
- sex hormone-binding globulin measurement · score 0.32
- neurofibrillary tangles measurement · score 0.26
- bone quantitative ultrasound measurement · score 0.26
- brain measurement · score 0.16
- arterial stiffness measurement · score 0.16
- autism · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A7XYQ1-F1 | alphafold | PREDICTED | 51.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A7XYQ1.
Amino-acid sequence (873 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SOBP?
The strongest Open Targets associations for SOBP are heel bone mineral density, body height, Intellectual disability, protein measurement and sex hormone-binding globulin measurement.
How long is the SOBP protein?
The Homo sapiens SOBP protein (UniProt A7XYQ1) is 873 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A7XYQ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A7XYQ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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