WASH complex subunit 1 (WASHC1)
Homo sapiens — UniProt A8K0Z3
Data last refreshed: (UniProt release unknown)
Key facts
WASH complex subunit 1 (WASHC1) is a protein from Homo sapiens identified by UniProt accession A8K0Z3, 465 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: A8K0Z3; gene symbol WASHC1.
- Organism: Homo sapiens.
- Length: 465 amino acids.
- Top disease associations (Open Targets): mean platelet volume, Red cell distribution width and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | WASH complex subunit 1 |
|---|---|
| UniProt accession | A8K0Z3 |
| Gene | WASHC1 |
| Organism | Homo sapiens |
| Length | 465 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.35
- Red cell distribution width · score 0.05
- platelet count · score 0.05
- platelet component distribution width · score 0.04
- fasting blood glucose measurement · score 0.03
- carpal tunnel syndrome · score 0.02
- heel bone mineral density · score 0.02
- infection · score 0.01
- infect · score 0.01
- ulcerative colitis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A8K0Z3-F1 | alphafold | PREDICTED | 65.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A8K0Z3.
Amino-acid sequence (465 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WASHC1?
The strongest Open Targets associations for WASHC1 are mean platelet volume, Red cell distribution width, platelet count, platelet component distribution width and fasting blood glucose measurement.
How long is the WASHC1 protein?
The Homo sapiens WASHC1 protein (UniProt A8K0Z3) is 465 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A8K0Z3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A8K0Z3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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