CMRF35-like molecule 7 (CD300LB)
Homo sapiens — UniProt A8K4G0
Data last refreshed: (UniProt release unknown)
Key facts
CMRF35-like molecule 7 (CD300LB) is a protein from Homo sapiens identified by UniProt accession A8K4G0, 201 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.
- UniProt accession: A8K4G0; gene symbol CD300LB.
- Organism: Homo sapiens.
- Length: 201 amino acids.
- Top disease associations (Open Targets): blood protein measurement, mucous membrane pemphigoid and monocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | CMRF35-like molecule 7 |
|---|---|
| UniProt accession | A8K4G0 |
| Gene | CD300LB |
| Organism | Homo sapiens |
| Length | 201 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (33)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.21
- mucous membrane pemphigoid · score 0.09
- monocyte count · score 0.07
- Balkan nephropathy · score 0.06
- monocyte percentage of leukocytes · score 0.06
- nephrotic syndrome, IIa 26 · score 0.05
- nephrotic syndrome 16 · score 0.04
- colitis · score 0.04
- myeloid white cell count · score 0.02
- Sepsis · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A8K4G0-F1 | alphafold | PREDICTED | 79.57 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A8K4G0.
Amino-acid sequence (201 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CD300LB?
The strongest Open Targets associations for CD300LB are blood protein measurement, mucous membrane pemphigoid, monocyte count, Balkan nephropathy and monocyte percentage of leukocytes.
How long is the CD300LB protein?
The Homo sapiens CD300LB protein (UniProt A8K4G0) is 201 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A8K4G0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A8K4G0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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