Uncharacterized protein C15orf62, mitochondrial (C15orf62)
Homo sapiens — UniProt A8K5M9
Data last refreshed: (UniProt release unknown)
Key facts
Uncharacterized protein C15orf62, mitochondrial (C15orf62) is a protein from Homo sapiens identified by UniProt accession A8K5M9, 175 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: A8K5M9; gene symbol C15orf62.
- Organism: Homo sapiens.
- Length: 175 amino acids.
- Top disease associations (Open Targets): mean platelet volume, esophageal adenocarcinoma and Barrett's esophagus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Uncharacterized protein C15orf62, mitochondrial |
|---|---|
| UniProt accession | A8K5M9 |
| Gene | C15orf62 |
| Organism | Homo sapiens |
| Length | 175 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.05
- esophageal adenocarcinoma · score 0.03
- Barrett's esophagus · score 0.03
- esophageal squamous cell carcinoma · score 0.03
- mean corpuscular volume · score 0.03
- Red cell distribution width · score 0.03
- triglyceride measurement · score 0.02
- sex hormone-binding globulin measurement · score 0.02
- metabolite measurement · score 0.02
- waist-hip ratio · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A8K5M9-F1 | alphafold | PREDICTED | 60.76 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A8K5M9.
Amino-acid sequence (175 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C15orf62?
The strongest Open Targets associations for C15orf62 are mean platelet volume, esophageal adenocarcinoma, Barrett's esophagus, esophageal squamous cell carcinoma and mean corpuscular volume.
How long is the C15orf62 protein?
The Homo sapiens C15orf62 protein (UniProt A8K5M9) is 175 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A8K5M9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A8K5M9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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