Zinc finger protein 785 (ZNF785)
Homo sapiens — UniProt A8K8V0
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 785 (ZNF785) is a protein from Homo sapiens identified by UniProt accession A8K8V0, 405 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: A8K8V0; gene symbol ZNF785.
- Organism: Homo sapiens.
- Length: 405 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, lysosomal storage disease and multiple sclerosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 785 |
|---|---|
| UniProt accession | A8K8V0 |
| Gene | ZNF785 |
| Organism | Homo sapiens |
| Length | 405 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.36
- lysosomal storage disease · score 0.13
- multiple sclerosis · score 0.13
- Parkinson disease · score 0.13
- Alzheimer disease · score 0.13
- sex hormone-binding globulin measurement · score 0.09
- alkaline phosphatase measurement · score 0.04
- monocyte count · score 0.03
- heel bone mineral density · score 0.03
- platelet count · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A8K8V0-F1 | alphafold | PREDICTED | 63.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A8K8V0.
Amino-acid sequence (405 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF785?
The strongest Open Targets associations for ZNF785 are neurodegenerative disease, lysosomal storage disease, multiple sclerosis, Parkinson disease and Alzheimer disease.
How long is the ZNF785 protein?
The Homo sapiens ZNF785 protein (UniProt A8K8V0) is 405 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A8K8V0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A8K8V0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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