BBSome-interacting protein 1 (BBIP1)

About BBSome-interacting protein 1

BBSome-interacting protein 1 (BBIP1) is a protein from Homo sapiens identified by UniProt accession A8MTZ0, 92 residues long. MolForge cross-references it against 0 known binders and 57 disease associations.

Target properties

Protein name	BBSome-interacting protein 1
UniProt accession	A8MTZ0
Gene	BBIP1
Organism	Homo sapiens
Length	92 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (57)

Diseases linked to this target (Open Targets).

Bardet-Biedl syndrome · score 0.54
type 2 diabetes mellitus · score 0.35
Specific learning disability · score 0.33
Narrow forehead · score 0.33
obesity · score 0.33
Micropenis · score 0.33
Postaxial hand polydactyly · score 0.33
Downslanted palpebral fissures · score 0.33
Round face · score 0.33
hypogonadotropic hypogonadism · score 0.33

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A8MTZ0-F1	alphafold	PREDICTED	81.82	—

Amino-acid sequence (92 residues)

MLKAAAKRPE LSGKNTISNN SDMAEVKSMF REVLPKQGPL FVEDIMTMVL CKPKLLPLKS LTLEKLEKMH QAAQNTIRQQ EMAEKDQRQI TH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards