BBSome-interacting protein 1 (BBIP1)
Homo sapiens — UniProt A8MTZ0
Data last refreshed: (UniProt release unknown)
Key facts
BBSome-interacting protein 1 (BBIP1) is a protein from Homo sapiens identified by UniProt accession A8MTZ0, 92 residues long. MolForge cross-references it against 0 known binders and 57 disease associations.
- UniProt accession: A8MTZ0; gene symbol BBIP1.
- Organism: Homo sapiens.
- Length: 92 amino acids.
- Top disease associations (Open Targets): Bardet-Biedl syndrome, type 2 diabetes mellitus and Specific learning disability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BBSome-interacting protein 1 |
|---|---|
| UniProt accession | A8MTZ0 |
| Gene | BBIP1 |
| Organism | Homo sapiens |
| Length | 92 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (57)
Diseases linked to this target (Open Targets).
- Bardet-Biedl syndrome · score 0.54
- type 2 diabetes mellitus · score 0.35
- Specific learning disability · score 0.33
- Narrow forehead · score 0.33
- obesity · score 0.33
- Micropenis · score 0.33
- Postaxial hand polydactyly · score 0.33
- Downslanted palpebral fissures · score 0.33
- Round face · score 0.33
- hypogonadotropic hypogonadism · score 0.33
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A8MTZ0-F1 | alphafold | PREDICTED | 81.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A8MTZ0.
Amino-acid sequence (92 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BBIP1?
The strongest Open Targets associations for BBIP1 are Bardet-Biedl syndrome, type 2 diabetes mellitus, Specific learning disability, Narrow forehead and obesity.
How long is the BBIP1 protein?
The Homo sapiens BBIP1 protein (UniProt A8MTZ0) is 92 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A8MTZ0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A8MTZ0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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