Sperm microtubule associated protein 1 (SPMAP1)
Homo sapiens — UniProt A8MV24
Data last refreshed: (UniProt release unknown)
Key facts
Sperm microtubule associated protein 1 (SPMAP1) is a protein from Homo sapiens identified by UniProt accession A8MV24, 154 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.
- UniProt accession: A8MV24; gene symbol SPMAP1.
- Organism: Homo sapiens.
- Length: 154 amino acids.
- Top disease associations (Open Targets): appendicular lean mass, waist-hip ratio and BMI-adjusted waist-hip ratio.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sperm microtubule associated protein 1 |
|---|---|
| UniProt accession | A8MV24 |
| Gene | SPMAP1 |
| Organism | Homo sapiens |
| Length | 154 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (5)
Diseases linked to this target (Open Targets).
- appendicular lean mass · score 0.04
- waist-hip ratio · score 0.02
- BMI-adjusted waist-hip ratio · score 0.02
- serum gamma-glutamyl transferase measurement · score 0.02
- Mobius syndrome · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A8MV24-F1 | alphafold | PREDICTED | 76.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A8MV24.
Amino-acid sequence (154 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPMAP1?
The strongest Open Targets associations for SPMAP1 are appendicular lean mass, waist-hip ratio, BMI-adjusted waist-hip ratio, serum gamma-glutamyl transferase measurement and Mobius syndrome.
How long is the SPMAP1 protein?
The Homo sapiens SPMAP1 protein (UniProt A8MV24) is 154 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A8MV24 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A8MV24 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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