MIF4G domain-containing protein (MIF4GD)
Homo sapiens — UniProt A9UHW6
Data last refreshed: (UniProt release unknown)
Key facts
MIF4G domain-containing protein (MIF4GD) is a protein from Homo sapiens identified by UniProt accession A9UHW6, 222 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: A9UHW6; gene symbol MIF4GD.
- Organism: Homo sapiens.
- Length: 222 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, age-related macular degeneration and testosterone measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | MIF4G domain-containing protein |
|---|---|
| UniProt accession | A9UHW6 |
| Gene | MIF4GD |
| Organism | Homo sapiens |
| Length | 222 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.29
- age-related macular degeneration · score 0.08
- testosterone measurement · score 0.08
- hematocrit · score 0.08
- non-alcoholic fatty liver disease · score 0.07
- hemoglobin measurement · score 0.07
- reticulocyte measurement · score 0.07
- X-linked retinal dysplasia · score 0.07
- choroidal dystrophy, central areolar, 1 · score 0.06
- Familial exudative vitreoretinopathy · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-A9UHW6-F1 | alphafold | PREDICTED | 91.77 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for A9UHW6.
Amino-acid sequence (222 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MIF4GD?
The strongest Open Targets associations for MIF4GD are neurodegenerative disease, age-related macular degeneration, testosterone measurement, hematocrit and non-alcoholic fatty liver disease.
How long is the MIF4GD protein?
The Homo sapiens MIF4GD protein (UniProt A9UHW6) is 222 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB A9UHW6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB A9UHW6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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