Unconventional myosin-Ig (MYO1G)
Homo sapiens — UniProt B0I1T2
Data last refreshed: (UniProt release unknown)
Key facts
Unconventional myosin-Ig (MYO1G) is a protein from Homo sapiens identified by UniProt accession B0I1T2, 1018 residues long. MolForge cross-references it against 0 known binders and 120 disease associations.
- UniProt accession: B0I1T2; gene symbol MYO1G.
- Organism: Homo sapiens.
- Length: 1018 amino acids.
- Top disease associations (Open Targets): lymphocyte count, leukocyte count and neutrophil count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Unconventional myosin-Ig |
|---|---|
| UniProt accession | B0I1T2 |
| Gene | MYO1G |
| Organism | Homo sapiens |
| Length | 1018 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (120)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.41
- leukocyte count · score 0.41
- neutrophil count · score 0.40
- monocyte percentage of leukocytes · score 0.35
- myeloid white cell count · score 0.31
- basophil count · score 0.23
- lymphocyte:monocyte ratio · score 0.23
- unipolar depression · score 0.20
- bipolar disorder · score 0.20
- inflammatory bowel disease · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-B0I1T2-F1 | alphafold | PREDICTED | 88.26 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for B0I1T2.
Amino-acid sequence (1018 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MYO1G?
The strongest Open Targets associations for MYO1G are lymphocyte count, leukocyte count, neutrophil count, monocyte percentage of leukocytes and myeloid white cell count.
How long is the MYO1G protein?
The Homo sapiens MYO1G protein (UniProt B0I1T2) is 1018 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB B0I1T2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB B0I1T2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.