Spermatogenesis-associated protein 31C2 (SPATA31C2)
Homo sapiens — UniProt B4DYI2
Data last refreshed: (UniProt release unknown)
Key facts
Spermatogenesis-associated protein 31C2 (SPATA31C2) is a protein from Homo sapiens identified by UniProt accession B4DYI2, 1134 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: B4DYI2; gene symbol SPATA31C2.
- Organism: Homo sapiens.
- Length: 1134 amino acids.
- Top disease associations (Open Targets): body height, psoriasis and sitting height measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Spermatogenesis-associated protein 31C2 |
|---|---|
| UniProt accession | B4DYI2 |
| Gene | SPATA31C2 |
| Organism | Homo sapiens |
| Length | 1134 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- body height · score 0.36
- psoriasis · score 0.24
- sitting height measurement · score 0.24
- longitudinal alcohol consumption measurement · score 0.23
- forced expiratory volume · score 0.20
- lean body mass · score 0.15
- BMI-adjusted hip circumference · score 0.12
- fat body mass · score 0.11
- base metabolic rate measurement · score 0.10
- appendicular lean mass · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-B4DYI2-F1 | alphafold | PREDICTED | 40.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for B4DYI2.
Amino-acid sequence (1134 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPATA31C2?
The strongest Open Targets associations for SPATA31C2 are body height, psoriasis, sitting height measurement, longitudinal alcohol consumption measurement and forced expiratory volume.
How long is the SPATA31C2 protein?
The Homo sapiens SPATA31C2 protein (UniProt B4DYI2) is 1134 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB B4DYI2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB B4DYI2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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