Transmembrane protein 150C (TMEM150C)

About Transmembrane protein 150C

Transmembrane protein 150C (TMEM150C) is a protein from Homo sapiens identified by UniProt accession B9EJG8, 249 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.

Target properties

Protein name	Transmembrane protein 150C
UniProt accession	B9EJG8
Gene	TMEM150C
Organism	Homo sapiens
Length	249 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (49)

Diseases linked to this target (Open Targets).

eosinophil count · score 0.18
myeloid white cell count · score 0.17
monocyte count · score 0.16
leukocyte count · score 0.15
basophil count · score 0.14
lymphocyte count · score 0.14
neutrophil count · score 0.14
type 2 diabetes mellitus · score 0.13
neutrophil percentage of leukocytes · score 0.12
eosinophil percentage of leukocytes · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-B9EJG8-F1	alphafold	PREDICTED	91.70	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for B9EJG8.

Amino-acid sequence (249 residues)

MDGKKCSVWM FLPLVFTLFT SAGLWIVYFI AVEDDKILPL NSAERKPGVK HAPYISIAGD DPPASCVFSQ VMNMAAFLAL VVAVLRFIQL KPKVLNPWLN ISGLVALCLA SFGMTLLGNF QLTNDEEIHN VGTSLTFGFG TLTCWIQAAL TLKVNIKNEG RRVGIPRVIL SASITLCVVL YFILMAQSIH MYAARVQWGL VMCFLSYFGT FAVEFRHYRY EIVCSEYQEN FLSFSESLSE ASEYQTDQV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards