Putative uncharacterized protein C5orf58 (C5orf58)
Homo sapiens — UniProt C9J3I9
Data last refreshed: (UniProt release unknown)
Key facts
Putative uncharacterized protein C5orf58 (C5orf58) is a protein from Homo sapiens identified by UniProt accession C9J3I9, 81 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: C9J3I9; gene symbol C5orf58.
- Organism: Homo sapiens.
- Length: 81 amino acids.
- Top disease associations (Open Targets): mean platelet volume, breast carcinoma and eosinophil count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Putative uncharacterized protein C5orf58 |
|---|---|
| UniProt accession | C9J3I9 |
| Gene | C5orf58 |
| Organism | Homo sapiens |
| Length | 81 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.26
- breast carcinoma · score 0.17
- eosinophil count · score 0.14
- immunodeficiency 81 · score 0.12
- eosinophil percentage of leukocytes · score 0.12
- Age-related cataract · score 0.02
- metastatic melanoma · score 0.01
- hepatocellular carcinoma · score 0.01
- sarcoma · score 0.01
- cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-C9J3I9-F1 | alphafold | PREDICTED | 76.21 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for C9J3I9.
Amino-acid sequence (81 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C5orf58?
The strongest Open Targets associations for C5orf58 are mean platelet volume, breast carcinoma, eosinophil count, immunodeficiency 81 and eosinophil percentage of leukocytes.
How long is the C5orf58 protein?
The Homo sapiens C5orf58 protein (UniProt C9J3I9) is 81 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB C9J3I9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB C9J3I9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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