Putative uncharacterized protein C19orf81 (C19orf81)
Homo sapiens — UniProt C9J6K1
Data last refreshed: (UniProt release unknown)
Key facts
Putative uncharacterized protein C19orf81 (C19orf81) is a protein from Homo sapiens identified by UniProt accession C9J6K1, 198 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: C9J6K1; gene symbol C19orf81.
- Organism: Homo sapiens.
- Length: 198 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, hypotrichosis simplex and Alopecia-intellectual disability syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Putative uncharacterized protein C19orf81 |
|---|---|
| UniProt accession | C9J6K1 |
| Gene | C19orf81 |
| Organism | Homo sapiens |
| Length | 198 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- hypotrichosis simplex · score 0.07
- Alopecia-intellectual disability syndrome · score 0.06
- primary familial polycythemia due to EPO receptor mutation · score 0.05
- Alopecia universalis · score 0.05
- uncombable hair syndrome · score 0.05
- wooly hair, autosomal recessive 3 · score 0.05
- hypotrichosis 4 · score 0.05
- hemolytic anemia due to diphosphoglycerate mutase deficiency · score 0.05
- smoking status measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-C9J6K1-F1 | alphafold | PREDICTED | 79.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for C9J6K1.
Amino-acid sequence (198 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C19orf81?
The strongest Open Targets associations for C19orf81 are neurodegenerative disease, hypotrichosis simplex, Alopecia-intellectual disability syndrome, primary familial polycythemia due to EPO receptor mutation and Alopecia universalis.
How long is the C19orf81 protein?
The Homo sapiens C19orf81 protein (UniProt C9J6K1) is 198 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB C9J6K1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB C9J6K1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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