UBAP1-MVB12-associated (UMA)-domain containing protein 1 (UMAD1)
Homo sapiens — UniProt C9J7I0
Data last refreshed: (UniProt release unknown)
Key facts
UBAP1-MVB12-associated (UMA)-domain containing protein 1 (UMAD1) is a protein from Homo sapiens identified by UniProt accession C9J7I0, 137 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.
- UniProt accession: C9J7I0; gene symbol UMAD1.
- Organism: Homo sapiens.
- Length: 137 amino acids.
- Top disease associations (Open Targets): neuroticism measurement, interstitial lung disease and urate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | UBAP1-MVB12-associated (UMA)-domain containing protein 1 |
|---|---|
| UniProt accession | C9J7I0 |
| Gene | UMAD1 |
| Organism | Homo sapiens |
| Length | 137 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- neuroticism measurement · score 0.41
- interstitial lung disease · score 0.27
- urate measurement · score 0.25
- bone density · score 0.25
- toxic epidermal necrolysis · score 0.23
- Stevens-Johnson syndrome · score 0.23
- monocyte percentage of leukocytes · score 0.19
- basophil count · score 0.10
- body height · score 0.08
- neutrophil count · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-C9J7I0-F1 | alphafold | PREDICTED | 61.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for C9J7I0.
Amino-acid sequence (137 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UMAD1?
The strongest Open Targets associations for UMAD1 are neuroticism measurement, interstitial lung disease, urate measurement, bone density and toxic epidermal necrolysis.
How long is the UMAD1 protein?
The Homo sapiens UMAD1 protein (UniProt C9J7I0) is 137 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB C9J7I0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB C9J7I0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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