Mapk-regulated corepressor-interacting protein 1 (MCRIP1)
Homo sapiens — UniProt C9JLW8
Data last refreshed: (UniProt release unknown)
Key facts
Mapk-regulated corepressor-interacting protein 1 (MCRIP1) is a protein from Homo sapiens identified by UniProt accession C9JLW8, 97 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.
- UniProt accession: C9JLW8; gene symbol MCRIP1.
- Organism: Homo sapiens.
- Length: 97 amino acids.
- Top disease associations (Open Targets): hematocrit, self reported educational attainment and surfactant metabolism dysfunction, pulmonary, 1.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mapk-regulated corepressor-interacting protein 1 |
|---|---|
| UniProt accession | C9JLW8 |
| Gene | MCRIP1 |
| Organism | Homo sapiens |
| Length | 97 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- hematocrit · score 0.16
- self reported educational attainment · score 0.10
- surfactant metabolism dysfunction, pulmonary, 1 · score 0.06
- Neonatal acute respiratory distress with surfactant metabolism deficiency · score 0.06
- Congenital pulmonary alveolar proteinosis · score 0.05
- idiopathic pulmonary fibrosis · score 0.05
- chronic respiratory distress with surfactant metabolism deficiency · score 0.05
- respiratory distress syndrome in premature infants · score 0.05
- autoimmune pulmonary alveolar proteinosis · score 0.04
- bronchopulmonary dysplasia · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-C9JLW8-F1 | alphafold | PREDICTED | 75.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for C9JLW8.
Amino-acid sequence (97 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MCRIP1?
The strongest Open Targets associations for MCRIP1 are hematocrit, self reported educational attainment, surfactant metabolism dysfunction, pulmonary, 1, Neonatal acute respiratory distress with surfactant metabolism deficiency and Congenital pulmonary alveolar proteinosis.
How long is the MCRIP1 protein?
The Homo sapiens MCRIP1 protein (UniProt C9JLW8) is 97 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB C9JLW8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB C9JLW8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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