Transmembrane protein 232 (TMEM232)
Homo sapiens — UniProt C9JQI7
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 232 (TMEM232) is a protein from Homo sapiens identified by UniProt accession C9JQI7, 657 residues long. MolForge cross-references it against 0 known binders and 118 disease associations.
- UniProt accession: C9JQI7; gene symbol TMEM232.
- Organism: Homo sapiens.
- Length: 657 amino acids.
- Top disease associations (Open Targets): asthma, allergic disease and allergic rhinitis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 232 |
|---|---|
| UniProt accession | C9JQI7 |
| Gene | TMEM232 |
| Organism | Homo sapiens |
| Length | 657 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (118)
Diseases linked to this target (Open Targets).
- asthma · score 0.41
- allergic disease · score 0.39
- allergic rhinitis · score 0.39
- seasonal allergic rhinitis · score 0.37
- eosinophil count · score 0.34
- atopic eczema · score 0.33
- neuropathy, hereditary motor and sensory, type 6B · score 0.33
- neuropathy, hereditary motor and sensory, type vib · score 0.33
- Eczematoid dermatitis · score 0.32
- childhood onset asthma · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-C9JQI7-F1 | alphafold | PREDICTED | 73.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for C9JQI7.
Amino-acid sequence (657 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM232?
The strongest Open Targets associations for TMEM232 are asthma, allergic disease, allergic rhinitis, seasonal allergic rhinitis and eosinophil count.
How long is the TMEM232 protein?
The Homo sapiens TMEM232 protein (UniProt C9JQI7) is 657 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB C9JQI7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB C9JQI7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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