Small integral membrane protein 47 (SMIM47)
Homo sapiens — UniProt D0EPY3
Data last refreshed: (UniProt release unknown)
Key facts
Small integral membrane protein 47 (SMIM47) is a protein from Homo sapiens identified by UniProt accession D0EPY3, 28 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.
- UniProt accession: D0EPY3; gene symbol SMIM47.
- Organism: Homo sapiens.
- Length: 28 amino acids.
- Top disease associations (Open Targets): amelogenesis imperfecta, type ij, Hypoplastic amelogenesis imperfecta and amelogenesis imperfecta.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small integral membrane protein 47 |
|---|---|
| UniProt accession | D0EPY3 |
| Gene | SMIM47 |
| Organism | Homo sapiens |
| Length | 28 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (3)
Diseases linked to this target (Open Targets).
- amelogenesis imperfecta, type ij · score 0.49
- Hypoplastic amelogenesis imperfecta · score 0.49
- amelogenesis imperfecta · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-D0EPY3-F1 | alphafold | PREDICTED | 93.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for D0EPY3.
Amino-acid sequence (28 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SMIM47?
The strongest Open Targets associations for SMIM47 are amelogenesis imperfecta, type ij, Hypoplastic amelogenesis imperfecta and amelogenesis imperfecta.
How long is the SMIM47 protein?
The Homo sapiens SMIM47 protein (UniProt D0EPY3) is 28 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB D0EPY3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB D0EPY3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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