Nuclear pore complex-interacting protein family member B11 (NPIPB11)
Homo sapiens — UniProt E5RHQ5
Data last refreshed: (UniProt release unknown)
Key facts
Nuclear pore complex-interacting protein family member B11 (NPIPB11) is a protein from Homo sapiens identified by UniProt accession E5RHQ5, 1161 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.
- UniProt accession: E5RHQ5; gene symbol NPIPB11.
- Organism: Homo sapiens.
- Length: 1161 amino acids.
- Top disease associations (Open Targets): Young adult-onset Parkinsonism, erythrocyte count and lymphocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nuclear pore complex-interacting protein family member B11 |
|---|---|
| UniProt accession | E5RHQ5 |
| Gene | NPIPB11 |
| Organism | Homo sapiens |
| Length | 1161 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (6)
Diseases linked to this target (Open Targets).
- Young adult-onset Parkinsonism · score 0.19
- erythrocyte count · score 0.05
- lymphocyte count · score 0.03
- psychosis · score 0.02
- neoplasm · score 0.01
- mood disorder · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-E5RHQ5-F1 | alphafold | PREDICTED | 40.12 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for E5RHQ5.
Amino-acid sequence (1161 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NPIPB11?
The strongest Open Targets associations for NPIPB11 are Young adult-onset Parkinsonism, erythrocyte count, lymphocyte count, psychosis and neoplasm.
How long is the NPIPB11 protein?
The Homo sapiens NPIPB11 protein (UniProt E5RHQ5) is 1161 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB E5RHQ5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB E5RHQ5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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