Anomalous homeobox protein (ANHX)
Homo sapiens — UniProt E9PGG2
Data last refreshed: (UniProt release unknown)
Key facts
Anomalous homeobox protein (ANHX) is a protein from Homo sapiens identified by UniProt accession E9PGG2, 379 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: E9PGG2; gene symbol ANHX.
- Organism: Homo sapiens.
- Length: 379 amino acids.
- Top disease associations (Open Targets): cardiovascular disease, mean platelet volume and hypertension.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Anomalous homeobox protein |
|---|---|
| UniProt accession | E9PGG2 |
| Gene | ANHX |
| Organism | Homo sapiens |
| Length | 379 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- cardiovascular disease · score 0.18
- mean platelet volume · score 0.15
- hypertension · score 0.13
- mean corpuscular volume · score 0.07
- type 2 diabetes mellitus · score 0.06
- mean corpuscular hemoglobin concentration · score 0.06
- BMI-adjusted waist-hip ratio · score 0.03
- platelet count · score 0.03
- mean corpuscular hemoglobin · score 0.03
- Abnormality of refraction · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-E9PGG2-F1 | alphafold | PREDICTED | 67.40 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for E9PGG2.
Amino-acid sequence (379 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANHX?
The strongest Open Targets associations for ANHX are cardiovascular disease, mean platelet volume, hypertension, mean corpuscular volume and type 2 diabetes mellitus.
How long is the ANHX protein?
The Homo sapiens ANHX protein (UniProt E9PGG2) is 379 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB E9PGG2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB E9PGG2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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