Nuclear pore complex-interacting protein family member B8 (NPIPB8)
Homo sapiens — UniProt E9PQR5
Data last refreshed: (UniProt release unknown)
Key facts
Nuclear pore complex-interacting protein family member B8 (NPIPB8) is a protein from Homo sapiens identified by UniProt accession E9PQR5, 432 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.
- UniProt accession: E9PQR5; gene symbol NPIPB8.
- Organism: Homo sapiens.
- Length: 432 amino acids.
- Top disease associations (Open Targets): neuroimaging measurement, brain measurement and brain volume measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nuclear pore complex-interacting protein family member B8 |
|---|---|
| UniProt accession | E9PQR5 |
| Gene | NPIPB8 |
| Organism | Homo sapiens |
| Length | 432 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (63)
Diseases linked to this target (Open Targets).
- neuroimaging measurement · score 0.26
- brain measurement · score 0.22
- brain volume measurement · score 0.21
- base metabolic rate measurement · score 0.20
- body fat percentage · score 0.19
- self reported educational attainment · score 0.19
- alcohol consumption measurement · score 0.16
- whole body water mass · score 0.16
- lean body mass · score 0.16
- body mass index · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-E9PQR5-F1 | alphafold | PREDICTED | 52.13 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for E9PQR5.
Amino-acid sequence (432 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NPIPB8?
The strongest Open Targets associations for NPIPB8 are neuroimaging measurement, brain measurement, brain volume measurement, base metabolic rate measurement and body fat percentage.
How long is the NPIPB8 protein?
The Homo sapiens NPIPB8 protein (UniProt E9PQR5) is 432 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB E9PQR5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB E9PQR5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.