Cation channel sperm-associated auxiliary subunit eta (CATSPERH)
Homo sapiens — UniProt E9PQX1
Data last refreshed: (UniProt release unknown)
Key facts
Cation channel sperm-associated auxiliary subunit eta (CATSPERH) is a protein from Homo sapiens identified by UniProt accession E9PQX1, 116 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: E9PQX1; gene symbol CATSPERH.
- Organism: Homo sapiens.
- Length: 116 amino acids.
- Target class: Ion channel.
- Top disease associations (Open Targets): high density lipoprotein cholesterol measurement, otosclerosis and visual perception measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cation channel sperm-associated auxiliary subunit eta |
|---|---|
| UniProt accession | E9PQX1 |
| Gene | CATSPERH |
| Organism | Homo sapiens |
| Length | 116 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Ion channel (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- high density lipoprotein cholesterol measurement · score 0.16
- otosclerosis · score 0.07
- visual perception measurement · score 0.03
- mean corpuscular volume · score 0.02
- osteosarcoma · score 0.02
- psoriasis · score 0.01
- juvenile dermatomyositis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-E9PQX1-F1 | alphafold | PREDICTED | 84.99 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for E9PQX1.
Amino-acid sequence (116 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CATSPERH?
The strongest Open Targets associations for CATSPERH are high density lipoprotein cholesterol measurement, otosclerosis, visual perception measurement, mean corpuscular volume and osteosarcoma.
How long is the CATSPERH protein?
The Homo sapiens CATSPERH protein (UniProt E9PQX1) is 116 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB E9PQX1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB E9PQX1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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