SLCO1B3-SLCO1B7 readthrough transcript protein (SLCO1B3-SLCO1B7)
Homo sapiens — UniProt F5H094
Data last refreshed: (UniProt release unknown)
Key facts
SLCO1B3-SLCO1B7 readthrough transcript protein (SLCO1B3-SLCO1B7) is a protein from Homo sapiens identified by UniProt accession F5H094, 687 residues long. MolForge cross-references it against 0 known binders and 96 disease associations.
- UniProt accession: F5H094; gene symbol SLCO1B3-SLCO1B7.
- Organism: Homo sapiens.
- Length: 687 amino acids.
- Top disease associations (Open Targets): bilirubin measurement, sex hormone-binding globulin measurement and serum alanine aminotransferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SLCO1B3-SLCO1B7 readthrough transcript protein |
|---|---|
| UniProt accession | F5H094 |
| Gene | SLCO1B3-SLCO1B7 |
| Organism | Homo sapiens |
| Length | 687 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (96)
Diseases linked to this target (Open Targets).
- bilirubin measurement · score 0.69
- sex hormone-binding globulin measurement · score 0.52
- serum alanine aminotransferase measurement · score 0.46
- serum gamma-glutamyl transferase measurement · score 0.42
- aspartate aminotransferase measurement · score 0.41
- ceramide measurement · score 0.32
- testosterone measurement · score 0.28
- mean platelet volume · score 0.28
- serum metabolite measurement · score 0.28
- acylcarnitine measurement · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-F5H094-F1 | alphafold | PREDICTED | 81.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for F5H094.
Amino-acid sequence (687 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLCO1B3-SLCO1B7?
The strongest Open Targets associations for SLCO1B3-SLCO1B7 are bilirubin measurement, sex hormone-binding globulin measurement, serum alanine aminotransferase measurement, serum gamma-glutamyl transferase measurement and aspartate aminotransferase measurement.
How long is the SLCO1B3-SLCO1B7 protein?
The Homo sapiens SLCO1B3-SLCO1B7 protein (UniProt F5H094) is 687 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB F5H094 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB F5H094 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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