Nuclear pore complex-interacting protein family member B9 (NPIPB9)
Homo sapiens — UniProt F8W1W9
Data last refreshed: (UniProt release unknown)
Key facts
Nuclear pore complex-interacting protein family member B9 (NPIPB9) is a protein from Homo sapiens identified by UniProt accession F8W1W9, 432 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: F8W1W9; gene symbol NPIPB9.
- Organism: Homo sapiens.
- Length: 432 amino acids.
- Top disease associations (Open Targets): body mass index, physical activity measurement and sex hormone-binding globulin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nuclear pore complex-interacting protein family member B9 |
|---|---|
| UniProt accession | F8W1W9 |
| Gene | NPIPB9 |
| Organism | Homo sapiens |
| Length | 432 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- body mass index · score 0.05
- physical activity measurement · score 0.04
- sex hormone-binding globulin measurement · score 0.04
- smoking behavior · score 0.03
- body fat percentage · score 0.03
- platelet count · score 0.03
- tonsillectomy risk measurement · score 0.02
- mean corpuscular volume · score 0.02
- intelligence · score 0.02
- alcohol consumption measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-F8W1W9-F1 | alphafold | PREDICTED | 49.36 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for F8W1W9.
Amino-acid sequence (432 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NPIPB9?
The strongest Open Targets associations for NPIPB9 are body mass index, physical activity measurement, sex hormone-binding globulin measurement, smoking behavior and body fat percentage.
How long is the NPIPB9 protein?
The Homo sapiens NPIPB9 protein (UniProt F8W1W9) is 432 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB F8W1W9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB F8W1W9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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