Keratin-associated protein 4-16 (KRTAP4-16)
Homo sapiens — UniProt G5E9R7
Data last refreshed: (UniProt release unknown)
Key facts
Keratin-associated protein 4-16 (KRTAP4-16) is a protein from Homo sapiens identified by UniProt accession G5E9R7, 235 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: G5E9R7; gene symbol KRTAP4-16.
- Organism: Homo sapiens.
- Length: 235 amino acids.
- Top disease associations (Open Targets): body mass index, lean body mass and fat body mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Keratin-associated protein 4-16 |
|---|---|
| UniProt accession | G5E9R7 |
| Gene | KRTAP4-16 |
| Organism | Homo sapiens |
| Length | 235 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- body mass index · score 0.12
- lean body mass · score 0.11
- fat body mass · score 0.09
- waist circumference · score 0.09
- body weight · score 0.08
- whole body water mass · score 0.07
- base metabolic rate measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-G5E9R7-F1 | alphafold | PREDICTED | 45.02 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for G5E9R7.
Amino-acid sequence (235 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KRTAP4-16?
The strongest Open Targets associations for KRTAP4-16 are body mass index, lean body mass, fat body mass, waist circumference and body weight.
How long is the KRTAP4-16 protein?
The Homo sapiens KRTAP4-16 protein (UniProt G5E9R7) is 235 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB G5E9R7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB G5E9R7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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