Transmembrane protein 250 (TMEM250)
Homo sapiens — UniProt H0YL14
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 250 (TMEM250) is a protein from Homo sapiens identified by UniProt accession H0YL14, 139 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.
- UniProt accession: H0YL14; gene symbol TMEM250.
- Organism: Homo sapiens.
- Length: 139 amino acids.
- Top disease associations (Open Targets): urate measurement, metastatic melanoma and meningeal tuberculosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 250 |
|---|---|
| UniProt accession | H0YL14 |
| Gene | TMEM250 |
| Organism | Homo sapiens |
| Length | 139 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (3)
Diseases linked to this target (Open Targets).
- urate measurement · score 0.07
- metastatic melanoma · score 0.01
- meningeal tuberculosis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-H0YL14-F1 | alphafold | PREDICTED | 74.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for H0YL14.
Amino-acid sequence (139 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM250?
The strongest Open Targets associations for TMEM250 are urate measurement, metastatic melanoma and meningeal tuberculosis.
How long is the TMEM250 protein?
The Homo sapiens TMEM250 protein (UniProt H0YL14) is 139 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB H0YL14 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB H0YL14 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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