Small lysine-rich protein 1 (SMKR1)
Homo sapiens — UniProt H3BMG3
Data last refreshed: (UniProt release unknown)
Key facts
Small lysine-rich protein 1 (SMKR1) is a protein from Homo sapiens identified by UniProt accession H3BMG3, 65 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: H3BMG3; gene symbol SMKR1.
- Organism: Homo sapiens.
- Length: 65 amino acids.
- Top disease associations (Open Targets): metabolite measurement, hemoglobin measurement and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small lysine-rich protein 1 |
|---|---|
| UniProt accession | H3BMG3 |
| Gene | SMKR1 |
| Organism | Homo sapiens |
| Length | 65 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- metabolite measurement · score 0.13
- hemoglobin measurement · score 0.10
- mean platelet volume · score 0.08
- non-small cell lung carcinoma · score 0.02
- colorectal adenocarcinoma · score 0.01
- hepatocellular carcinoma · score 0.01
- astrocytoma · score 0.01
- cancer · score 0.00
- colorectal cancer · score 0.00
- gonorrhea · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-H3BMG3-F1 | alphafold | PREDICTED | 71.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for H3BMG3.
Amino-acid sequence (65 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SMKR1?
The strongest Open Targets associations for SMKR1 are metabolite measurement, hemoglobin measurement, mean platelet volume, non-small cell lung carcinoma and colorectal adenocarcinoma.
How long is the SMKR1 protein?
The Homo sapiens SMKR1 protein (UniProt H3BMG3) is 65 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB H3BMG3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB H3BMG3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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