Stathmin domain-containing protein 1 (STMND1)
Homo sapiens — UniProt H3BQB6
Data last refreshed: (UniProt release unknown)
Key facts
Stathmin domain-containing protein 1 (STMND1) is a protein from Homo sapiens identified by UniProt accession H3BQB6, 276 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: H3BQB6; gene symbol STMND1.
- Organism: Homo sapiens.
- Length: 276 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, mathematical ability and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Stathmin domain-containing protein 1 |
|---|---|
| UniProt accession | H3BQB6 |
| Gene | STMND1 |
| Organism | Homo sapiens |
| Length | 276 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.48
- mathematical ability · score 0.44
- neurodegenerative disease · score 0.40
- DNA methylation · score 0.32
- unipolar depression · score 0.27
- generalised epilepsy · score 0.25
- gastroesophageal reflux disease · score 0.22
- intelligence · score 0.22
- age at first birth measurement · score 0.22
- cognitive function measurement · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-H3BQB6-F1 | alphafold | PREDICTED | 63.11 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for H3BQB6.
Amino-acid sequence (276 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with STMND1?
The strongest Open Targets associations for STMND1 are self reported educational attainment, mathematical ability, neurodegenerative disease, DNA methylation and unipolar depression.
How long is the STMND1 protein?
The Homo sapiens STMND1 protein (UniProt H3BQB6) is 276 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB H3BQB6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB H3BQB6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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