POTE ankyrin domain family member B2 (POTEB2)
Homo sapiens — UniProt H3BUK9
Data last refreshed: (UniProt release unknown)
Key facts
POTE ankyrin domain family member B2 (POTEB2) is a protein from Homo sapiens identified by UniProt accession H3BUK9, 544 residues long. MolForge cross-references it against 0 known binders and 1 disease associations.
- UniProt accession: H3BUK9; gene symbol POTEB2.
- Organism: Homo sapiens.
- Length: 544 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | POTE ankyrin domain family member B2 |
|---|---|
| UniProt accession | H3BUK9 |
| Gene | POTEB2 |
| Organism | Homo sapiens |
| Length | 544 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (1)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-H3BUK9-F1 | alphafold | PREDICTED | 71.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for H3BUK9.
Amino-acid sequence (544 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with POTEB2?
The strongest Open Targets associations for POTEB2 are neurodegenerative disease.
How long is the POTEB2 protein?
The Homo sapiens POTEB2 protein (UniProt H3BUK9) is 544 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB H3BUK9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB H3BUK9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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