RING finger protein 225 (RNF225)
Homo sapiens — UniProt M0QZC1
Data last refreshed: (UniProt release unknown)
Key facts
RING finger protein 225 (RNF225) is a protein from Homo sapiens identified by UniProt accession M0QZC1, 329 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.
- UniProt accession: M0QZC1; gene symbol RNF225.
- Organism: Homo sapiens.
- Length: 329 amino acids.
- Top disease associations (Open Targets): esophageal adenocarcinoma, esophageal squamous cell carcinoma and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RING finger protein 225 |
|---|---|
| UniProt accession | M0QZC1 |
| Gene | RNF225 |
| Organism | Homo sapiens |
| Length | 329 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (5)
Diseases linked to this target (Open Targets).
- esophageal adenocarcinoma · score 0.03
- esophageal squamous cell carcinoma · score 0.03
- mean platelet volume · score 0.02
- papillary thyroid carcinoma · score 0.01
- attention deficit hyperactivity disorder · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-M0QZC1-F1 | alphafold | PREDICTED | 64.13 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for M0QZC1.
Amino-acid sequence (329 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RNF225?
The strongest Open Targets associations for RNF225 are esophageal adenocarcinoma, esophageal squamous cell carcinoma, mean platelet volume, papillary thyroid carcinoma and attention deficit hyperactivity disorder.
How long is the RNF225 protein?
The Homo sapiens RNF225 protein (UniProt M0QZC1) is 329 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB M0QZC1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB M0QZC1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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