Synaptosomal-associated protein 23 (SNAP23)
Homo sapiens — UniProt O00161
Data last refreshed: (UniProt release unknown)
Key facts
Synaptosomal-associated protein 23 (SNAP23) is a protein from Homo sapiens identified by UniProt accession O00161, 211 residues long. MolForge cross-references it against 0 known binders and 107 disease associations.
- UniProt accession: O00161; gene symbol SNAP23.
- Organism: Homo sapiens.
- Length: 211 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, erythrocyte count and hepatocellular carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Synaptosomal-associated protein 23 |
|---|---|
| UniProt accession | O00161 |
| Gene | SNAP23 |
| Organism | Homo sapiens |
| Length | 211 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (107)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- erythrocyte count · score 0.18
- hepatocellular carcinoma · score 0.18
- sex hormone-binding globulin measurement · score 0.18
- red blood cell density measurement · score 0.18
- hemoglobin measurement · score 0.17
- mean corpuscular volume · score 0.14
- squamous cell lung carcinoma · score 0.12
- ringed hair disease · score 0.08
- Griscelli syndrome type 3 · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-O00161-F1 | alphafold | PREDICTED | 82.11 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for O00161.
Amino-acid sequence (211 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNAP23?
The strongest Open Targets associations for SNAP23 are neurodegenerative disease, erythrocyte count, hepatocellular carcinoma, sex hormone-binding globulin measurement and red blood cell density measurement.
How long is the SNAP23 protein?
The Homo sapiens SNAP23 protein (UniProt O00161) is 211 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB O00161 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB O00161 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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